MMB-CHMICA (Methyl N-[1-(cyclohexylmethyl)-1H-indole-3-carbonyl] valinate) is a novel synthetic cannabinoid. It is an indole-based synthetic molecule which contains an isopropyl ...More
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MMB-CHMICA (Methyl N-[1-(cyclohexylmethyl)-1H-indole-3-carbonyl] valinate) is a novel
synthetic cannabinoid. It is an indole-based synthetic molecule which contains an isopropyl
instead of t-butyl group in MDMB-CHMICA. Also, it shares some structural similarities with
AB-CHMINACA – both of them are indole derivatives.
MMB-CHMICA increases the activity of dopaminergic neurons in the ventral tegmental area-
mesolimbic pathway, so it shares a final common neuronal action with other substances such as
morphine, ethanol and nicotine in producing facilitation of the mesolimbic dopamine system.
This compound acts as a highly potent full agonist of the CB1 receptor and an EC50 value of
0.14 nM, which is approximately 8 times lower than the EC50 of JWH-018 (1.13 nM) and two
fold lower than AB-CHMINACA (0.27 nM).
Effects may include euphoria, feeling of well-being, increased appreciation of the arts, a
general alteration of conscious perception, metacognition or introspection, increase sensuality,
libido and creativity, increased sensuality, but sometimes it can lead to dissociative states such
as depersonalization or derealization.
Physical effects may include a rapid increase of the heart-rate.
MMB-CHMICA (C22H30N2O3, Mr 370g/mol) generally comes in the form of a white to skin-color powder.
Always store in a cool, dry place for maximum shelf-life.
This product is intended for forensic and research applications only. It is therefore NOT intended for human consumption or in-vivo testing of any kind on animals or any living organism.