Piracetam

What Is Piracetam? Piracetam is the oldest and most well-studied nootropic. This safe and well-tolerated racetam has been used as a ‘smart drug’ by individuals all around the ...More

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What Is Piracetam?

Piracetam is the oldest and most well-studied nootropic. This safe and well-tolerated racetam has been used as a ‘smart drug’ by individuals all around the world because of its reported cognitive enhancement properties.

What is piracetam powder used for?

In regards to the first question, Piracetam powder is most commonly purchased by individuals looking to enhance their cognitive abilities, specifically memory, intelligence, and attention.

What is piracetam prescribed for?

While the substance is not approved by the FDA, it is prescribed in the UK for the treatment of a muscle spasm disorder called myoclonus and in Europe as a treatment for specific types of seizure disorders. Many physicians throughout the world have used it as an off label treatment for Alzheimers as some studies have shown it to slow the process of mental decline observed in Alzheimer's patients.

Piracetam Chemical Properties

Piracetam, more formally known as 2-oxo-1-pyrrolidine-acetamide, is a compound that shares chemical properties with other substances in the Racetam class. Although its exact mechanism of actions is not well understood, it is known to be a positive allosteric of the AMPA receptor in the brain. Because of this, many researchers have hypothesized that piracetam leads to increased neuronal excitability and thus improved cognitive functions. There is also significant evidence to show that piracetam increases oxygen and blood flow to certain areas of the brain, including the hippocampus, the area of the brain most associated with learning and memory.

Studies have also demonstrated Piracetama's ability to increase the neurotransmitter acetylcholine, which neuroscientists heavily correlate with memory development and the learning process. The amount in which the substance is able to influence the previously mentioned processes depends largely on the individual and the piracetam dosage taken.

How to Take Piracetam?

Piracetam comes as a powder that users either put into gel capsules or mix into a cup of water. Because of its poor taste, the former is the preferred method. It is common for Piracetam users to also take a Choline source, such as Choline L-Bitartrate, with Piracetam as there are reported synergistic effects.

Piracetam dosage is a topic of much debate within the smart drug community and how much piracetam to take does not have a definite answer. Typically, users take anywhere between 400 mg - 1,600 mg two to three times a day. Some people report experiencing positive effects at lower doses while other users report needing doses as high as 4 grams/day to begin to feel the effects. The vast majority of users go through a trial phase where they are experimenting with different dosages in hopes of finding what works best for them. Some studies have shown that piracetam has a U-shaped dose-response rate, meaning that many users report decreased effects at certain dosage thresholds. The standard practice has been to start at doses of 500mg three times a day and work up from there until the desired effect has been achieved.

Benefits Of Using Piracetam

Increased Cognitive Function: While there are many clinical applications for Piracetam, the vast majority of Piracetam consumed worldwide is as a smart drug to improve cognitive function. Numerous studies have shown the compound's positive effects of memory, learning, verbal intelligence [1] [2] [3]. There are still many questions regarding exactly how does piracetam work, but controlled peer-reviewed studies have demonstrated the benefits of piracetam.

Slows Cognitive Decline: Neurological disorders are particularly difficult because the individuals slowly lose their cognitive abilities and, in some cases, their sense of self. Piracetam has been investigated, and prescribed, to sufferers of Alzheimers and Dementia because it has been shown to be effective in lessening the cognitive decline associated with these conditions [4].

Treatment Of Neurological Disorders: As previously mentioned, Piracetam has been used in the treatment of epilepsy and dyslexia with a fair amount of success [5] [6]. There is also evidence to suggest that Piracetam benefits those suffering from of Demyelinating diseases [7]

Improved Memory: The largest group of Piracetam users are healthy individuals who take the substance for its memory-enhancing properties [8] [9]. This is by far the most commonly reported effect amongst users consuming the substance as a smart drug.

What Are Warnings And Possible Side Effects

Piracetam is a very well tolerated substance and users rarely report side effects. When they do occur, piracetam side effects are usually limited to anxiety, insomnia, drowsiness, agitation, and headaches.

When researchers are evaluating the safety profile of a substance, they attempt to determine its median lethal dose or LD50. The LD50 of piracetam has not been established and studies have shown it to be well tolerated in doses as high as 24grams/day, although this is well beyond the recommended daily dose. Negative side effects of piracetam are considered to be mild at worst and go away once the individual discontinues their use of the substance.

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