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What is Sulbutiamine? Sulbutiamine, also known as Arcalion, is a synthetic made derivative of thiamine which most know as vitamin B1, however, Sulbutiamine is commonly described a...More

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What is Sulbutiamine?

Sulbutiamine, also known as Arcalion, is a synthetic made derivative of thiamine which most know as vitamin B1, however, Sulbutiamine is commonly described as the upgraded version of vitamin B1 as it has a higher bioavailability than thiamine and therefore can pass through the blood-brain barrier far easier and can then supply your brain with the much-needed vitamin B1. It was first discovered by Japanese scientists in an effort to develop useful thiamine derivatives.

Sulbutiamine has a lot of great effects on the body and mind. Here are a few things you can expect to benefit from by using this fantastic Vitamin B1 derivative:

Memory enhancement

Sulbutiamine helps regulate levels of acetylcholine, a neurotransmitter that plays a critical role in memory formation, short-term memory, and long-term memory.

Motivation Booster

Research shows that through boosting dopamine and glutamate levels in your prefrontal cortex Sulbutiamine can give you the mood and motivation boost you need.

Decreases fatigue

Several different studies show that it helps boost energy in a similar way to caffeine, so instead of the 10th cup of coffee, reach for your daily dose of Sulbutiamine.

Benefits of Sulbutiamine

Alzheimer’s Disease

Early research into Sulbutiamine shows that when combined with Alzheimer’s medication for periods of 3 months and more the supplement can improve the attention span and showed signs of prolonging the memory.

Depression

Sulbutiamine was administered in an 8 week multicentric, randomized, double-blind, placebo-controlled trial, conducted by ‘Loo et al’. The trial showed that when administering 600mg/day of Sulbutiamine significantly decreased social inhibition associated with the depressive event incurred by the subject. This gives a great example of how Nootropics can and are changing the world as we know it.

Diabetic Nerve Pain

Research has shown that Sulbutiamine, when administered for periods longer than 6 weeks, improves how well the nerves work in people with nerve damage caused by diabetes. The supplement does not seem to improve symptoms of diabetic nerve pain but has been shown to help give back some precious time of those nerves.

Chemical Properties of Sulbutiamine

Sulbutiamine is a synthetic derivative of thiamine usually under the market name of Arcalion that is composed of two modified thiamine molecules to form a dimer. Being highly lipophilic, it is able to pass the blood-brain barrier easier than other thiamine derivatives. This makes it a better source of Vitamin B1 than other derivatives.

IUPAC:

[(E)-4-[(4-amino-2-methylpyrimidin-5-yl)methyl-formylamino]-3-[[(E)-2-[(4-amino-2-methylpyrimidin-5-yl)methyl-formylamino]-5-(2-methylpropanoyloxy)pent-2-en-3-yl]disulfanyl]pent-3-enyl] 2-methylpropanoate

CAS No: 3286-46-2

Molecular Formula: C32H46N8O6S2

Molecular Weight: 702.9 g/mol

Note

Sulbutiamine has now had a few in-depth studies in humans. We have seen that there are a few side effects you can expect when taking it in doses larger than recommended: diarrhea, arthritic pain, Insomnia, headaches, kidney pain, sore throat, and constipation. Sulbutiamine is approved for human consumption, but please be sure to monitor your dosage and keep a close eye on your personal well-being when taking it regularly. We suggest using gloves and a mask when making up your dosages to ensure extra ingestion does not happen.

Where to buy Sulbutiamine?

Here at Chemical Planet, you can always purchase the best quality chemicals. This nootropic powder is no exception to that. Sulbutiamine comes in powder form at the moment, but we may look into producing it in other forms. You can contact our customer service to find out updates about that. Besides, we are always open to feedback, so if we don't have something you are after, please let us know. When buying Nootropics online, you can be sure to be getting the very best here at Chemical Planet. However, If you would like to buy Sulbutiamine from Chemical Planet, you must be at least 18 years of age.

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